Local Keyboard Assignments/probably user error
Probably user Error to be honest, but this worked be for the patch now it dose not seem to I have a corsair mouse with 12 buttons I use basically as a mouse over macro on Vuhdo and use the same buttons to DPS if i am not mousing over the Vuhdo interface. 
I tried a new profile and setting them up from scratch but it dose not seem to work probably not a bug but i cant seem to figure out what i might be doing wrong.